Hurdles in Basic Science Translation

Hurdles in Basic Science Translation

In the past century there have been incredible advances in the field of medical research, but what hinders translation of this knowledge into effective treatment for human disease? There is an increasing focus on the failure of many research breakthroughs to be translated through the clinical trial process and into medical practice. In this mini review, we will consider some of the reasons that...

Advances in basic science.

Basic science continues to occupy a substantial portion of the program at the Conference on Retroviruses and Opportunistic Infections. At the 17th conference this year, presentations focused on advances in our understanding of cellular factors that regulate the interplay between the virus and the host cell and, in particular, cellular defenses such as tetherin (or BST-2) that antagonize viral r...

Basic Facts for Basic Science

Overall, this outstanding text should soon become recognized as the definitive reference for the diagnosis and management of ocular trauma. The tall, narrow shape of Basic Facts for Basic Science suggests that perhaps the author intended that it be put into the pocket of one's lab coat; perhaps not, but this book is certainly appropriate for the shelf of any laboratory and for the office of any...

How basic is basic science?

Some other possible conclusions come easily to mind. Perhaps, if we’re really concerned about students’ learning evidence-based medicine, then we should teach it more or better. On the other hand I am one of many who have joined the anti-EBM movement (Norman 1999). In my view, the fundamental irony remains that, even though it made the BMJ’s ‘‘Top 15 Medical Innovations of all Time’’ list in 20...

Basic Science